UNIX does not have :File Equations, mostly because it does not have file attributes, but it does have symbolic links which allow more than one name for the same file.
When something mysterious happens with an MPE file, use the :Listeq command to check for :File equations and the :Listftemp command to check for temporary files. Although all :File parameters correspond to some FOPEN or FCLOSE parameters, not all FOPEN and FCLOSE parameters can be redefined with :File. For instance, you cannot redefine the number of user labels or the flag indicating whether to retain space between the end-of-file and the file-limit on close.